Spironolactone

• 

Name:

Spironolactone

EINECS:

200-133-6

Molecular Formula:

C₂₄H₃₂O₄S

CAS Registry Number:

52-01-7

Synonyms:

Alderon; 3-(3-Keto-7.alpha.-acetylthio-17.beta.-hydroxy-4-androsten-17.alph a.-yl)propionic acid lactone; Uractone; Spiro(17H-cyclopenta(a)phenauthrene-17,2-(3H)-furan); Xenalon; Pregn-4-ene-21-carboxylic acid,7-(acetylthio)-17-hydroxy-3-oxo-,?- lactone,(7R,17R)-; Aldactone; 17.alpha.-Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7.alpha.-mercapto-3-oxo-, .gamma.-lactone, acetate; Euteberol; Prestwick_449; Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)-; Spironolactone A; Urusonin; Verospirone; SC 9420; SC 15983; Spiro(17H-cyclopenta(a)phenanthrene-17,2(5H)-furan), pregn-4-ene-21-carboxylic acid deriv.; Spiro-Tablinen; Spirolang; Spironolactone [BAN:INN:JAN]; 7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone; 7-alpha-(acetylthio)-17-alpha-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, gamma-lactone (9CI); ; Spironolactonum [INN-Latin]; Aldactone A; Aldactazide (TN); Spiroctan; 3-(3-Oxo-7-alpha-acetylthio-17-beta-hydroxyandrost-4-en-17-beta-yl)propionic acid lactone; 7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid gamma-lactone; Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, g-lactone, (7a,17a)-; Verospiron;

InChI:

InChI=1/C24H32O4S/c,/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1

Molecular Structure:

This structure is also available as a2d Mol file

Chemical Properties

Appearance:

White powder.

Molecular Weight:

416.57

Density:

1.24g/cm³

Boiling Point:

597℃ at 760mmHg

Melting Point:

198-207℃

Flash Point:

302.3℃

Alpha:

-37 ° (C=1, CHCL3)

Storage Temperature:

Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.

Refractive index:

-36 ° (C=1, CHCl3)

Solubility:

practically insoluble

Biological Activity:

Competitive mineralocorticoid (aldosterone) receptor antagonist that exhibits antihypertensive activity in vivo . Also displays antiandrogen activity and inhibits steroid hormone biosynthesis.

Stability:

Stable under normal temperatures and pressures.

Usage:

It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypok.

Other supplier products

	tripotassium citrate	Name:tripotassium citrateEINECS:212-755-5;231-905-0Molecular Formula:C6H5K3O7CAS Registry Number:866-84-2;7778-49-6Synonyms:tri-Potassium citrate; ...
	Nitrobenzaldehyde	Name: 2-Nitrobenzaldehyde EINECS: 209-025-3 Molecular Formula: C7H5NO3 CAS Registry Number: 552-89-6 Synonyms: 2-Nitobenzaldehyde; 2-Nitrobenzaldeh...
	Ethacridine lactate monohydrate	Name: Ethacridine lactate monohydrate EINECS: 217-408-1 Molecular Formula: C15H15N3O.C3H6O3.H2O CAS Registry Number: 6402-23-9 ...
	Chitosan	Name: Chitosan EINECS: 222-311-2 Molecular Formula: Unspecified CAS Registry Number: 9012-76-4 Synonyms: Flonac C; Chitosan ...
	Montmorillonite	Name:MontmorilloniteEINECS:215-288-5Molecular Formula:Al2O9Si3CAS Registry Number:1318-93-0Synonyms:Montmorillonite(8CI); AMS (mineral); Albagen 4...

Same products

	MONSA® DDAC-50	Seller: Guangzhou Monsa Chemical Co., Ltd	INCI name: MONSA® DDAC-50 It functions by causing the cell membrane of bacteria to rupture...
	MONSA® DCA-50	Seller: Guangzhou Monsa Chemical Co., Ltd	INCI name: disodium cocoampho diacetate Disodium cocoamphodiacetate for skinis a very mild amp...
	MONSA® CTAC-50	Seller: Guangzhou Monsa Chemical Co., Ltd	INCI name: Cetyl Trimethyl Ammonium Chloride Cetyl Trimethyl Ammonium Chloride is an ammonium ...
	MONSA® CTAC-30	Seller: Guangzhou Monsa Chemical Co., Ltd	INCI name: Cetyl Trimethyl Ammonium Chloride 30% Cetyltrimethyl ammonium chloride30% is mainly...
	Common Rail Injector	Seller: DIP (DIESEL INJECTION PARTS) PLANTS	Item: Diesel Fuel Injector　　　　　　　　　 Model No: MOQ: 1pc　　　　　　　　　　　　　　　　Material: SteelPackage Deta...