Hormone Therapy Treat Breast Cancer in Postmenopausal Women by Anastrozole

Hormone Therapy Treat Breast Cancer in Postmenopausal Women by Anastrozole
Anastrozole is also called Arimidex. It is a type of hormone therapy called an aromatase inhibitor. Anastrozole treats breast cancer in women who have had their menopause.
Arimidex may sometimes be used to treat breast cancer in men.
Anastrozole CAS: 120511-73-1
Chemical data
Formula C17H19N5
Mol. mass 293.366 g/mol

How anastrozole works
Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers can be treated with drugs that block the effects of these hormones.
In women who have had their menopause, oestrogen is mainly produced by changing androgens (sex hormones produced by the adrenal glands) into oestrogens. This process is called aromatisation and happens mainly in the fatty tissues, muscle and the skin. It needs a particular enzyme called aromatase.
Arimidex blocks the process of aromatisation. So it lowers the amount of oestrogen in the body. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.

Usage in men
Anastrozole has been tested for reducing estrogens, including estradiol, in men. Excess estradiol in men can cause benign prostatic hyperplasia, gynecomastia, and symptoms of hypogonadism.
Some athletes and body builders use anastrozole as part of their steroid cycle to reduce and prevent symptoms of excess estrogen--gynecomastia, emotional lability and water retention.

STORAGE: Store anastrozole tablets at room temperature, between 20 C - 25 C (68 F - 77 F).

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