factory supply Tamoxifen citrate CAS 54965-24-1 kessar noltam tamofen(Email:sophia525@yccreate.com)

factory supply Tamoxifen citrate CAS 54965-24-1 kessar noltam tamofen(Email:sophia525@yccreate.com)
Appearance:white powder
Molecular Formula: C32H37NO8
Specification: CP/USP/EP
Molecular Weight: 563.64
Solubility: slightly soluble
Melting point: 140-144 °C
Storage Condition: 2-8°C
Model No.: C32H34NO8
Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, 4-hydroxytamoxifen. In other tissues such as theendometrium, it behaves as an agonist, and thus may be characterized as a mixed agonist/antagonist. Tamoxifen is the usual endocrine(anti-estrogen) therapy for hormone receptor-positive breast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting.

Some breast cancer cells require estrogen to grow. Estrogen binds to and activates the estrogen receptor in these cells. Tamoxifen is metabolized into compounds that also bind to the estrogen receptor but do not activate it. Because of this competitive antagonism, tamoxifen acts like a key broken off in the lock that prevents any other key from being inserted, preventing estrogen from binding to its receptor. Hence breast cancer cell growth is blocked.

Tamoxifen was discovered by pharmaceutical company Imperial Chemical Industries(now AstraZeneca) and is sold under the trade names Nolvadex,Istubal, and Valodex. However, the drug has been widely referred to by its generic name "tamoxifen", even before its patent expiration.

It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.




Send product request

To: Wuhan Yuancheng Gongchuang Technology Co., Ltd.
Your E-mail:
Message text:


Send to other suppliers

Other supplier products

Gardenia Blue
Gardenia Blue Gardenia Blue product Name Gardenia Blue Synonyms CCRIS 8305; Gardenia Blue Color CAS Registry Number 106441-42-3 Discriptions: It is a kind of nat...
Factory Supply High Purity Sarsaparilla Extract
Factory Supply High Purity Sarsaparilla Extract Factory Supply High Purity Sarsaparilla Extract Appearance: brown powder Functions and usage: According to Chinese records, Smilax can be used for ...
Factory Supply Okra extract (Email:sophia525@yccreate.com)
Factory Supply Okra extract (Email:sophia525@yccreate.com) Factory Supply Okra extract (Email:sophia525@yccreate.com) Appearance: Brown powder Functions:Okra extract can activate the central nervous men and...
Factory Supply Steroid Testosterone Phenylpropionate CAS NO.: 1255-49-8(Email:sophia525@yccreate.com)
Factory Supply Steroid Testosterone Phenylpropionate CAS NO.: 1255-49-8(Email:sophia525@yccreate.com) Factory Supply Steroid Testosterone Phenylpropionate CAS NO.: 1255-49-8(Email:sophia525@yccreate.com) Chemical Name: 4-Androsten-17β-ol-3-one ...
Schisandra extract   CAS: 7432-28-2
Schisandra extract CAS: 7432-28-2 Schisandra extract CAS: 7432-28-2 Molecular formula: C24H32O7 Molecular weight: 432.56 Appearance: Brown-yellow fine powder Purity: 3%(Alcohol...
All supplier products

Same products

Icariin/ Horny Goat Weed/ Epimedium Seller: Hubei Yuancheng Saichuang Technology Co., Ltd Icariin/ Horny Goat Weed/ Epimedium Chemical Name: EPIMEDIUM BRM (HORNY GOAT WEED) Appearance: Br...
Icariin/ Horny Goat Weed/ Epimedium Seller: Hubei Yuancheng Saichuang Technology Co., Ltd Icariin/ Horny Goat Weed/ Epimedium Chemical Name: EPIMEDIUM BRM (HORNY GOAT WEED) Appearance: Br...
Icariin/ Horny Goat Weed/ Epimedium Seller: Hubei Yuancheng Saichuang Technology Co., Ltd Icariin/ Horny Goat Weed/ Epimedium Chemical Name: EPIMEDIUM BRM (HORNY GOAT WEED) Appearance: Br...
Icariin/ Horny Goat Weed/ Epimedium Seller: Hubei Yuancheng Saichuang Technology Co., Ltd Icariin/ Horny Goat Weed/ Epimedium Chemical Name: EPIMEDIUM BRM (HORNY GOAT WEED) Appearance: Br...
Icariin/ Horny Goat Weed/ Epimedium Seller: Hubei Yuancheng Saichuang Technology Co., Ltd Icariin/ Horny Goat Weed/ Epimedium Chemical Name: EPIMEDIUM BRM (HORNY GOAT WEED) Appearance: Br...