IPO11 Antibody;HRP conjugated

Product Name:
IPO11 Antibody;HRP conjugated
Code : CSB-PA887057LB01HU
Immunogen : Recombinant human Importin-11 protein
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA;Not yet tested in other applications.
Relevance : Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).
Conjugate : HRP
Alias : Importin-11,Imp11,IPO11,RANBP11,Ran-binding protein 11,RanBP11

Cusabio is a biotech company. Our main products include recombinant proteins and antibodies, ELISA kits, raw materials for diagnostic reagents, food safety testing products.

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