Eptifibatide;? Sequence?

Product Name Eptifibatide;?
Sequence? Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2
Cas No. 148031-34-9
Molecular Formula C35H49N11O9S2
Molecular Weight 832.4
Appearance White slightly yellwish powder
Specific Rotation[20/D] -75.0~-95.0°(C=1,1%HAc) ?
Amino Acids composition ± 10%
Peptide Purity (By HPLC) ≥98% by area integration
Related Substance (By HPLC) Total Impurities (%)≤2.0%? Largest Single Impurity (%)≤ 1.0%
Water Content (Karl Fischer) ≤8.0%
Peptide Content(N determination) ≥80%
Acetate Content ≤15%
IR spectrum in accordance


Brief introduction:

Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.[1] Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri).

It belongs to the class of the so-called arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.

Indications

Eptifibatide is used to reduce the risk of acute cardiac ischemic events (death and/or myocardial infarction) in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment elevation acute coronary syndromes) both in patients who are to receive non surgery (conservative) medical treatment and those undergoing percutaneous coronary intervention (PCI).

The drug is usually applied together with aspirin or clopidogrel and (low molecular weight or unfractionated) heparin. Additionally, the usual supportive treatment consisting of applications of nitrates, beta-blockers, opioid analgesics and/or benzodiazepines should be employed as indicated. Angiographic evaluation and other intensive diagnostic procedures may be considered a first line task before initiating therapy with eptifibatide.

The drug should exclusively be used in hospitalized patients both because of the serious degree of patients' illness and because of the possible side-effects of eptifibatide.




Send product request

To: HuBei YuanCheng SaiChuang Technology Co.,Ltd
Your E-mail:
Message text:


Send to other suppliers

Other supplier products

Stanozolol(winstrol)
Stanozolol(winstrol) Stanozolol(winstrol) Chemical Name: 5alpha-androstan-17alpha methyl-17beta ol-[3,2-c] pyrazole CAS NO.: 10148-03-8 Molecular Formula: C21H32N2O Mol...
Product Name Secretin Acetate
Product Name Secretin Acetate Product Name Secretin Acetate Sequence H-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu- Ser-Arg-Leu-Arg-Asp-Ser-Ala-Arg-Leu-Gln- Arg-Leu-Leu-Gln-Gly-Leu-...
Testosterone Enanthate
Testosterone Enanthate Testosterone Enanthate Synonyms: testosterone enantate; testosterone enthanoate CAS Registry Number 315-37-7 Molecular Formula: C26H40O3 Molecular ...
Testosterone Decanoate
Testosterone Decanoate Testosterone Decanoate CAS NO.: 5721-91-5 Chemical Name: 4-Androsten-17beta-ol-3-one Decanoate Chemical Formula: C29H46O3 Description: white or yel...
Oxymetholone
Oxymetholone Oxymetholone Chemical Name: 5alpha-androstan-2-hydroxymethylene-17alpha-methyl-17beta-ol-3-one CAS NO.: 434-07-1 Molecular Formula: C21H32O3 Molecu...
All supplier products

Same products

Mibolerone
Mibolerone Seller: Guangzhou Kafen Biotech Co.,Ltd High Purity Raw Steroid Powder Mibolerone CAS 3704-09-4 For Muscle Building 1.Quick Details: Pr...
Lidocaine / Xylocaine
Lidocaine / Xylocaine Seller: Guangzhou Kafen Biotech Co.,Ltd Local Anesthetic Drugs Lidocaine / Xylocaine CAS 137-58-6 For Reducing Pain 1.Quick Detail: Pro...
Oxytocin
Oxytocin Seller: Guangzhou Kafen Biotech Co.,Ltd Polypeptide Hormone Oxytocin CAS 60786-59-6 For Muscle Growth And Anti-aging 1.Quick Detail: Pro...
gefitinib  ADB-chminaca 5F-MN24 2NMC MBC EEC  4-CEC,BK-EBPD
gefitinib ADB-chminaca 5F-MN24 2NMC MBC EEC 4-CEC,BK-EBPD Seller: kaiwodun CassieShu sales6@kaiwodun-pharma.com skype:kaiwodun06 4-cprc 3-cmc 4-cec Crystal Mmbc &n...
MDPT BMDP hen 4-CL-PMT 4-CL-PET 5f-ADB appp 4-CEC,BK-EBPD Seller: kaiwodun CassieShu sales6@kaiwodun-pharma.com skype:kaiwodun06 4-cprc 3-cmc 4-cec Crystal Mmbc &n...