Leuprolide Sequence?


Product Name Leuprolide
Sequence? pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt
Cas No. 53714-56-0
Purity (HPLC) Not less than 98%
Molecular Formula C59H84N16O12
Molecular Weight 1209.4
Appearance White or slightly yellowish white powder
Water ≤7.0%
Acetic acid ≤10.0%
IR spectrum in accordance


Applications:

Mainly has a strong angiotensin II vasoconstriction and increase in blood pressure. The mechanism is: 1. So that the body arteriole smooth muscle contraction, increased peripheral resistance; 2. So increase the release of adrenal aldosterone, causing sodium retention, increased blood volume; 3. Directly contribute to renal tubular sodium and water reabsorption; 4. So the brain central nervous sympathetic vasoconstrictor activity, causing increased peripheral vascular resistance; 5. Stimulate the adrenal medulla to release epinephrine and norepinephrine




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