Alarelin Acetate

Product Name Alarelin Acetate
Sequence Glp-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt
Cas No. 79561-22-1
Molecular Formula C56H78N16O12
Molecular Weight 1167.3
Purity (HPLC) 98%min.
Appearance White powder
Single Impurity(HPLC) 1.0%max
Amino Acid Composition ±10% of theoretical
Peptide Content(N%) ≥80.0%
Water Content(Karl Fischer) ≤8.0%
Acetate Content(HPIC) ≤12.0%
Specific Rotation (20/D) -37.0~-47.0°(c=1 1%HAc)
MS(ESI) Consistent
Mass Balance 95.0~105.0%

Description:

Alarelin (Gonadotrophin-releasing hormone) is a synthetic GnRH agonist. Alarelin is found in higher amounts than that of LH-RH in rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in ovulation inductions. Alarelin is known for its induction of ovulation and is used to treat endmometriosis. Alarelin Acetate is the acetate form of a hypothalamic peptide that stimulates the release of FSH and LH from the pituitary gland.
Alarelin acetate is a gondatrophin releasing hormone. Natural forms of alarelin found in animals are used to induce ovulation. Synthetic versions of this product are created using an LH-RH antagonist which is commonly set in larger doses than the natural LH-RH that is typically found in the rat hypophyseal stimulation or the gondatoropin secretions in induced ovulation or in vitro.
This chemical is the acetate form of the natural hypothalamic peptide which is used by an animal's body to release LH and FSH from the pituitary gland. The peptide alarelin acetate has a single non-glycosylated polypeptide structure that is made up of nine amino acids.?




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