Tetracaine hydrochloride


Tetracaine hydrochloride

Quick Detail:
Product Name: Tetracaine hydrochloride
Synonyms: L AND OCAIN HYDROCHLORIDE;
CAS: 136-47-0
MF: C15H25ClN2O2
MW: 300.82
EINECS: 205-248-5
Product Categories: Amines;Heterocycles;Intermediates & Fine
Chemicals;Pharmaceuticals;NUPERCAINAL;Other APIs
Packing:Foil bag or as requirments
2. Description:
Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
3. Application:
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
use:Used for mucosal epidermal anesthesia, nerve tissue anesthesia, epidural anesthesia and Subarachnoid space anesthesia.
In the manufacture of pharmaceutical preparation for external use, to relieve the pain of drugs or medication lesions pain.

 




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