Isotretinoin / Accutane for Treatment of Severe Acne 4759-48-2 

Isotretinoin (Accutane) is primarily used to treat bad cases of cystic acne, and to help the skin more rapidly renew itself. In addition, it is used in rare cases for certain skin cancers and skin diseases. It is a type of retinoid, which is naturally found in the body in small amounts. 
Name: Isotretinoin 

Basic info 
Synonym: 13-cis-ra;13-cis-retinoicaci;13-ra;accutane;Isoretinoin;isotrex;neovitaminaacid;ro-4-3780 
CAS: 4759-48-2 
MF: C20H28O2 
MW: 300.44 
EINECS: 225-296-0 
Assay: 99% 
Chemical Properties: Yellow-Orange Crystalline Powder 
Usage: Used as a treatment for severe acne. Presently being studied in conjuction with the treatment of photoaged skin. 
Usage: 5HT1a receptor agonist, anxiolytic 
Package: 100g/foil bag 

Accutane works as an isomer of Vitamin A, which reduces the amount of oil released by the oil glands in the skin; this will make it difficult for acne to form and reduce it significantly. Nearly all patients achieve clearing of acne during a course, with 90% reporting'excellent' results with higher dosages. 

Bodybuilders who use anabolic steroids have utilized accutane to counteract the negative effects of steroids on their skin; especially, the acne related side effects. 
Since chances of acne are increased with anabolic steroid use, and bodybuilding requires looking good (especially physique competitors), many athletes who have failed to conquer their acne with natural remedies will turn to accutane. 
It is the androgenic increases associated with steroids that will trigger increased acne. This is especially true for those genetically prone to the condition. Also, the hormonal changes can trigger acne as well, such as increased testosterone levels. 

Accutane Dosage 
Among bodybuilders, the dosage should be conservative. Once a day dose of 10-20mgs for 6-8 weeks maximum should work fine. Among the general public fighting acne, a dosage of 50-150mg per day may be prescribed by their physician. It is a good idea to take the drug with a large meal. In addition, it may be necessary to use multiple courses of treatment.

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