CAS 68-96-2 17A-hydroxyprogesterone


CAS 68-96-2 17A-hydroxyprogesterone

Natural Glucocorticoid 17A-hydroxyprogesterone White Crystalline Powder Cas 68-96-2

Product name: 17A-hydroxyprogesterone
CAS No.: 68-96-2
EINEC No.: 200-699-4
Molecular Formula: C21H30O3
Molecular weight: 330.4611
Packaging: 1kg/bag
Assay: 99%
Density: 1.15g/cm3
Melting point: 276 ℃
Boiling point: 482.9 ° C at 760 mmHg
Flash point: 259.9 ° C
Steam pressure: 2.37E-11mmHg at 25 ° C
Appearance: White or white crystalline powder
Usage: it is an important intermediate for the synthesis of steroid hormone and steroid progesterone drug. It can be synthesized by hydrocortisone, betamethasone, cortisone acetate, progesterone caproate, chlormadinone etc.

The 17-hydroxyprogesterone (17-OHP) test is routinely ordered as part of newborn screening in the UnitedStates to detect congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. CAH is a group ofinherited disorders caused by specific gene mutations and associated with cortisol-related enzymedeficiencies. About 90% of CAH cases are caused by a mutation in the 21-hydroxylase gene (also calledP450c1 or CYP21A2) and may be detected due to the accumulation of 17-OHP in the blood.

The 17-OHP test may be used to screen for CAH in older children or adults before symptoms appear or toconfirm a CAH diagnosis in people with symptoms.

17-OHP testing may produce false-positive test results. If the level is elevated but not so high that it isdiagnostic of CAH, other tests may be performed, such as androstenedione and testosterone. An ACTHstimulation test may be also be ordered as a follow-up test (in CAH, ACTH stimulation will markedlyincrease 17-OHP levels). Molecular genetic testing may be performed to detect CYP21A2 gene mutations thatcan cause the condition. A karyotype test may be ordered as a follow-up test to detect chromosome disordersand to help determine a baby's sex. Electrolytes may be ordered to measure the person's sodium andpotassium levels.


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Our advantages:
1)Saichuang Technology Co., ltd is a professional raw powder factory in China for over 10 years, all powders are factory directly supplying.
2)Our products have exported to Germany , Norway , Poland , Finland , Spain , UK , France ,Russia , USA , Australia , Japan , Korea and many other countries, over 100kgs each month.
3)Professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed. 100% pass to UK , Norway , Poland , Spain , USA , Canada , Brazil; 98% pass to Germany , Russia , Australia , New Zealand .
4)Most of powders are in stock, Chargeable samples are available, Could be shipped out within 24hours.
5)High quality, good price, fast and safety delivery.




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