CAS 37025-55-1 Carbetocin


CAS 37025-55-1 Carbetocin

Product Name:Duratocin,Carbetocin,Depotocin
Synonyma: Carbetocin; Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-PRO-Leu-Gly-NH2 (SulfidebondbetweenButyryl- 4-ylandCys
CAS No.: 37025-55-1
EINECS NO: 253-312-6
Molecular Formula: C45H69N11O12S
Molecular Weight: 988.17
Purity (HPLC)98%min.
Refractive index: 1.541
Melting point: 847.6º C º C
Grade: Pharmaceutical grade
Appearance White powder
Storage: Shading, confined preservation
Packaging: 2mg/5mg/10mg per vial or as required
Usage: Nutritional supplement


Application:

Carbetocin (trade names Duratocin, Pabal, Lonactene) is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section.

It is an eight amino long oxytocin analogue (oxytocin is a nonapeptide) and its action is similar to that of oxytocin. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.


Specifications:

Single Impurity (HPLC): 0.5%max
Amino Acid Composition: ± 10% of theoretical
Peptide Content (N%): ≥ 80.0%
Water Content (Karl Fischer): ≤ 8.0%
Acetate Content (HPIC): ≤ 10.0%
Specific Rotation (20/D): -55.0~-65.0° (c=11%HAc)
MS (ESI): Consistent
Mass Balance: 95.0~105.0%

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