CAS 86784-80-7


CAS 86784-80-7 Corticotropin releasing factor

Product name: CRF (HUMAN, RAT),corticotropinreleasing factor
CAS Registry Number: 86784-80-7
Molecular Formula:C208H344N60O63S2
Appearance: White Powder
Grade: Pharmaceutical Grade
Storage: Cool dry place (-20oC, away from light)

Application:

Corticotrophin Releasing Factor (Corticotropin Releasing Factor, CRF) is a kind of important neuroendocrine peptide, it can promote the synthesis and release of corticosteroids (glucocorticoids, GC), so as to regulate and control the hypothalamus - pituitary - adrenal axis (hypothalamic - pituitary - adrenal axis, HPA) function.





Application:

Carbetocin (trade names Duratocin, Pabal, Lonactene) is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section.

It is an eight amino long oxytocin analogue (oxytocin is a nonapeptide) and its action is similar to that of oxytocin. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.


Specifications:

Single Impurity (HPLC): 0.5%max
Amino Acid Composition: ± 10% of theoretical
Peptide Content (N%): ≥ 80.0%
Water Content (Karl Fischer): ≤ 8.0%
Acetate Content (HPIC): ≤ 10.0%
Specific Rotation (20/D): -55.0~-65.0° (c=11%HAc)
MS (ESI): Consistent
Mass Balance: 95.0~105.0%

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1)Saichuang Technology Co., ltd is a professional raw powder factory in China for over 10 years, all powders are factory directly supplying.
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