H3K9me1
As one of the professional custom peptide synthesis companiesin China, KS-V Peptide has been specialized in providing customized peptides synthesisservices(including Toxins and Analogues, Ubiquitins and Ubiquitin Probes, Post-translational Histones and other peptide manufacturing, APIs and process optimization of the pharmaceutical peptide.
SPECIFICATION OF H3K9ME1
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CAT |
H3104 |
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Product Name |
Histone H3-K9me1 |
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Purity |
≥95% by HPLC analysis |
|
Appearance |
White powder |
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Usage |
Research use only |
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Storage |
Shipping at room temperature. Upon delivery aliquot. Stored at -20°C or -80°C. Avoid freeze/thaw cycle. |
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Sequence |
ARTKQTARK(me1)STGGKAPRKQL ATKAARKSAP ATGGVKKPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA |
APPLICATION OF H3K9ME1
Monomethylation of histone H3 at lysine 9 (H3K9Me1) is found at euchromatin regions of silenced genes and is correlated with gene repression. Recognition of H3K9Me1 by the H3K9 demethylases GLP and G9a is essential to embryonic stem cell differentiation and viability in mice. Cytoplasmic localization of H3K9Me1 is associated with reduced disease-specific mortality risk in patients with oral and/or oropharyngeal squamous cell carcinoma.
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