CA242
CA242carbohydrate antigen is a kind of saliva acidification that can be colon cancer cell lines by a series of monoclonal antibody hybridoma technology is one of CA242 recognition.
Many organs of malignant tumor mucin types of a glycoprotein found it, called Cang, which cannot react with LewisA antigens and cannot react with saliva acidification galactose glucoside.
CA242 tumor markeris almost always expressed together with CA50, but different monoclonal antibodies recognize the two. Clinically, CA242 tumor marker has been using in the diagnosis of gastrointestinal malignancies, especially pancreatic and colorectal cancers.
Compared with CA19-9 and CA50, the new generation CA242 tumor markerhas higher sensitivity and specificity in the pancreatic, gallbladder, and gastrointestinal cancers.
CA242 Intro
Cancer antigen 242, a sialylated glycosphingolipid antigen, is a pancreatic and colon cancer marker. The increase is seen in 68% ~ 79% of pancreatic cancer, 55% ~ 85% of colon cancer, 44% of gastric cancer, and 5% ~ 33% of non-malignant tumors. Also, the positive rates of ovarian, uterine, and lung cancer were higher than CA50.
CA242 Blood Test
Cancer antigen 242 is a marker for the digestive system, especially colon, rectal and pancreatic cancer. It is superior to CA19-9 in diagnosing pancreatic cancer, with a sensitivity of 66% to 100%. It is also helpful for diagnosing liver cancer, gastric cancer, and esophageal cancer. However, ca242 blood test is not suitable for diagnosing squamous cell carcinoma.
Reference value: -12 units/ml (u/ml) (IRMA method).
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