Anastrozole Help Shrink Tumor and Slow Their Growth

Anastrozole Help Shrink Tumor and Slow Their Growth
Arimidex is a hormonal therapy used to treat breast cancer in women who have been through the menopause.
Hormones are substances produced naturally in the body. They act as chemical messengers and help control the activity of cells and organs. Hormonal therapies work by interfering with the production or action of particular hormones in the body.

Uses
This medication is used to treat breast cancer in women who have gone through "the change of life" (menopause). Anastrozole works by lowering estrogen hormone levels to help shrink tumors and slow their growth.

Aromatase inhibitors
Some breast cancer cells have receptors, which allow particular types of hormones to attach to the cancer cell. In order to grow, many breast cancers rely on the hormone oestrogen. These cancers are known as oestrogen receptor-positive or ER-positive breast cancers.

In women who have had their menopause, the main source of oestrogen is through the conversion of androgens (sex hormones produced by the adrenal glands) into oestrogens. This is carried out by an enzyme called aromatase. The conversion process is known as aromatisation, and it happens mainly in the fatty tissues of the body.

Arimidex is a drug that blocks the process of aromatisation, and so reduces the amount of oestrogen in the body. As less oestrogen reaches the cancer cells, they grow more slowly or stop growing altogether. Drugs that work in this way are known as aromatase inhibitors|. Other aromatase inhibitors include letrozole(Femara) and exemestane (Aromasin).

Many breast cancer tumors grow in response to estrogen. This medicine interferes with the production of estrogen in the body. As a result, the amount of estrogen that the tumor is exposed to is reduced, limiting the growth of the tumor.

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