99% Purity Lyophilized Peptide Bremelanotide PT-141 10mg/vial

99% Purity Lyophilized Peptide Bremelanotide PT-141 10mg/vial
Identifiers & Chemical data
Appearance: White Powder
CAS number: 189691-06-3
Formula: C50H68N14O10
Mol. mass: 1025.16 g/mol
Half-life: 120 minutes
Sequence: Ac-Nle-cyclo(Asp-His-D-Phe-Arg-Trp-Lys)-OH
Chain: CH3CO-Nle-[Asp-His-(d)-Phe-Arg-Trp-Lys]-COOH
Synonyms: Brmelanotice; BREMELANOTIDE PT141; BreMelanotide Acetate
Storage: Lyophilized PT-141 is stable at room temperature for 90 days, however it should be stored in a freezer below -8°C for any extended period of time. After reconstituting PT-141 should be refrigerated at temperatures not to exceed 36 F.

Development
Bremelanotide was developed from the peptide hormone Melanotan II which underwent testing as a sunless tanning agent. In initial testing, Melanotan II did induce tanning but additionally caused sexual arousal and spontaneous erections as unexpected side effects in nine out of the ten original male volunteer test subjects.

Structure
Bremelanotide is a cyclic hepta-peptide lactam analog of alpha-melanocyte-stimulating hormone (alpha-MSH) that activates the melanocortin receptors MC3-R and MC4-R in the central nervous system. It has the amino acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH or cyclo-[Nle4, Asp5, D-Phe7, Lys10]alpha-MSH-(4-10). It is a metabolite of Melanotan II that lacks the C-terminal amide function.

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