Recombinant human Lysyl oxidase homolog 1

Product Name:
Recombinant human Lysyl oxidase homolog 1
Product Type : Recombinant Protein
Code : CSB-EP013040HU
Size : 1mg
Uniprot NO. : Q08397
Research Area : Metabolism
Source : E.coli
Gene Names : LOXL1
Expression Region : 106-574aa
Product Info : His-tag
Mol. Weight : 55.8kD
Protein Description : Partial of the full length of 95-574aa
Target details : This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

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