factory supply high purity Tamoxifen citrate CAS 54965-24-1 kessar noltam tamofen

factory supply high purity Tamoxifen citrate CAS 54965-24-1 kessar noltam tamofen
Appearance:whit powder
Molecular Formula: C32H37NO8
Specification: CP/USP/EP
Molecular Weight: 563.64
Solubility: slightly soluble
Melting point: 140-144 °C
Storage Condition: 2-8°C
Model No.: C32H34NO8
Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, 4-hydroxytamoxifen. In other tissues such as theendometrium, it behaves as an agonist, and thus may be characterized as a mixed agonist/antagonist. Tamoxifen is the usual endocrine(anti-estrogen) therapy for hormone receptor-positive breast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting.

Some breast cancer cells require estrogen to grow. Estrogen binds to and activates the estrogen receptor in these cells. Tamoxifen is metabolized into compounds that also bind to the estrogen receptor but do not activate it. Because of this competitive antagonism, tamoxifen acts like a key broken off in the lock that prevents any other key from being inserted, preventing estrogen from binding to its receptor. Hence breast cancer cell growth is blocked.

Tamoxifen was discovered by pharmaceutical company Imperial Chemical Industries(now AstraZeneca) and is sold under the trade names Nolvadex,Istubal, and Valodex. However, the drug has been widely referred to by its generic name "tamoxifen", even before its patent expiration.

It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.



在线询价

至: Wuhan Yuancheng Gongchuang Technology Co., Ltd.
Your E-mail:
消息正文:


Send to other suppliers

Other supplier products

Mometasone Furoate
Mometasone Furoate
Factory Supply High Purity Steroid Powder Hydroxyprogesterone Acetate CAS No.: 302-23-8
Factory Supply High Purity Steroid Powder Hydroxyprogesterone Acetate CAS No.: 302-23-8
Glycerol monocaprylate
Glycerol monocaprylate
Potassium carbonate
Potassium carbonate
Maltose
Maltose
供应产品

Same products

Canned solid pack sliced apples 3000g/A10
Canned solid pack sliced apples 3000g/A10 卖方: Sanmenxia Yuanfeng Fruit industry Co.,Ltd
Canned apple sauce 3000g/A10
Canned apple sauce 3000g/A10 卖方: Sanmenxia Yuanfeng Fruit industry Co.,Ltd
Canned  yellow peach dices 3000g/A10
Canned yellow peach dices 3000g/A10 卖方: Sanmenxia Yuanfeng Fruit industry Co.,Ltd
Canned yellow peach dices 3000g/A10 卖方: Sanmenxia Yuanfeng Fruit industry Co.,Ltd
商业链条围栏
商业链条围栏 卖方: 岩链链条有限公司 商业链条围栏摆门 - 性价比高 商业摇摆门为公司。 CSG-01:商用双摆门。 公路,机场,工厂和体育领域都采用商业链条围栏门,单或双摆。与住宅栅栏门相比,商业门具有更强的织物,门柱和框架。一...