Leuprolide Sequence?

Product Name Lysipressin Acetate
Sequence
Cas No. 50-57-7
Molecular Formula C46H65N13O12 S2
Molecular Weight 1056.22
Purity (HPLC) 98.0%min.
Appearance? White powder
Single Impurity(HPLC)? 1.0%max
Amino Acid Composition? ±10% of theoretical
Peptide Content(N%) ?≥80.0%
Water Content(Karl Fischer)? ≤6.0%
Acetate Content(HPIC) ≤10.0%
MS(ESI) ?Consistent
Mass Balance? 95.0~105.0%


Applications:

Mainly has a strong angiotensin II vasoconstriction and increase in blood pressure. The mechanism is: 1. So that the body arteriole smooth muscle contraction, increased peripheral resistance; 2. So increase the release of adrenal aldosterone, causing sodium retention, increased blood volume; 3. Directly contribute to renal tubular sodium and water reabsorption; 4. So the brain central nervous sympathetic vasoconstrictor activity, causing increased peripheral vascular resistance; 5. Stimulate the adrenal medulla to release epinephrine and norepinephrine



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