CJC-1295 without DAC

Product Name Enfuvirtide Acetate (T-20)
Sequence CH3CO-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu
-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-
Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys
-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2
Cas No. 159519-65-0
Molecular Formula C204H301N51O64
Molecular Weight 4492
Purity (HPLC) 98.0%min.
Appearance? White to off-white amorphous solid
Single Impurity (HPLC)? 0.5%max
Amino Acid Composition? ±10% of theoretical
Peptide Content (N%) ≥80.0%
Water Content (Karl Fischer)? ≤8.0%
TrifluoroAcetate Content(HPIC) ≤12.0%
MS (ESI) Consistent
Mass Balance? 95.0~105.0%


2. Description:

Enfuvirtide is an antiretroviral drug used in combination therapy for the treatment of HIV-1/AIDS. It binds to the first heptad-repeat (HR1) in the gp41 subunit of the viral envelope glycoprotein and prevents the conformational changes required for the fusion of viral and cellular membranes. It works by disrupting



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