Bivalirudin Trifluoroacetate

供应商:

供应产品

Product Name

Bivalirudin Trifluoroacetate

Sequence

D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH

Cas No.

128270-60-0

Molecular Formula

C98H138N24O33

Molecular Weight

2180.33

Purity (HPLC)

98.0%min.

Appearance

White Powder

Single Impurity (HPLC)

1.0%max

Amino Acid Composition

±10% of theoretical

Peptide Content (N%)

≥80.0%

Water Content (Karl Fischer)

≤8.0%

TrifluoroAcetate Content(HPIC)

≤12.0%

MS (ESI)

Consistent

Mass Balance

95.0~105.0%

 

 

2. Description:
Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a specific and reversible direct thrombin inhibitor (DTI).
Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.
Bivalirudin clinical studies demonstrated consistent positive outcomes in patients with stable angina, unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) undergoing PCI in 7 major randomized trials.



在线询价

至:
Your E-mail:
消息正文:


Send to other suppliers

Other supplier products

Testosterone Phenylpropionate
Testosterone Phenylpropionate
Clostebol acetate
Clostebol acetate Clostebol acetate Alias: 4-chlorotestosterone acetate;  4-chloroandrost-4-ene-17beta-ol-3-one acetate CAS NO.: 855-19-6 Molecular Formula: C21...
Antide Acetate
Antide Acetate Product Name Antide Acetate Sequence Ac-D-2-Nal-p-Chloro-D-Phe-β-(3-pyridyl)-D-Ala-Ser-Lys(nicotinoyl)-D-Lys(nicotinoyl)-Leu-Lys(i...
Oral Durabolin , Nandrolone Phenylpropionate for Aplastic Anemia Treatment
Oral Durabolin , Nandrolone Phenylpropionate for Aplastic Anemia Treatment Basic Info Model NO.: 62-90-8 durabolin Specification: 99% Durabolin Trademark: Saichuang Origin: China Product Desc...
Discreet Packing and Safe Delivery Splenopentin Acetate
Discreet Packing and Safe Delivery Splenopentin Acetate Basic Info Model NO.: 105184-37-0 Grade Standard: Medicine Grade Trademark: Yuancheng Saichuang Origin: China Function:&n...
供应产品

Same products

ACRYLIC JAR - JTA01 卖方: Shaoxing Jinte Packaging Co., Ltd.
Auto Gas Springs for ALFA ROMEO 卖方: YUYAO PRETTY HOME SANITARY WARES CO., Ltd
mango extract 卖方: 湖南康隆生物科技股份有限公司
pvc-shower-curtain 卖方: Yuyao Pretty Home Sanitary Wares CO.,Ltd
Turmeric Curcuma extract 卖方: 湖南康隆生物科技股份有限公司