Bivalirudin Trifluoroacetate

供应商:

供应产品

Product Name

Bivalirudin Trifluoroacetate

Sequence

D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH

Cas No.

128270-60-0

Molecular Formula

C98H138N24O33

Molecular Weight

2180.33

Purity (HPLC)

98.0%min.

Appearance

White Powder

Single Impurity (HPLC)

1.0%max

Amino Acid Composition

±10% of theoretical

Peptide Content (N%)

≥80.0%

Water Content (Karl Fischer)

≤8.0%

TrifluoroAcetate Content(HPIC)

≤12.0%

MS (ESI)

Consistent

Mass Balance

95.0~105.0%

 

 

2. Description:
Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a specific and reversible direct thrombin inhibitor (DTI).
Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.
Bivalirudin clinical studies demonstrated consistent positive outcomes in patients with stable angina, unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) undergoing PCI in 7 major randomized trials.



在线询价

至:
Your E-mail:
消息正文:


Send to other suppliers

Other supplier products

Oxandrolone
Oxandrolone Detail       Oxandrolone Chemical Name: 5alpha-androstan-2-oxa-17alpha-methyl-17beta-ol-3-one CAS NO.: 53-39-4 Molecular Fo...
Finasteride
Finasteride Quick Detail   1 ) Finasteride 2 ) Alias: Proscar 3 ) CAS No: 98319-26-7 4 ) MF: C23H36N2O2 5 ) MW: 372.55       6 ) Purity: 9...
Testosterone Acetate
Testosterone Acetate Testosterone Acetate Other name:  testosterone acetate--dea schedule iii;  (17beta)-3-oxoandrost-4-en-17-yl acetate; 3-oxoandrost-4-en-17...
Betamethasone
Betamethasone Betamethasone Synonyms: Bifas; Bebate; Becort CAS: 378-44-9 Molecular formula: C22H29FO5   MW: 392.46 Packing: 5KG/TIN,2TIN/CTN Quality Standa...
Boldenone Undecylenate
Boldenone Undecylenate Boldenone Undecylenate CAS NO.: 13103-34-9 Molecular Formula: C30H44O3 Molecular weight: 452.67 Assay: 97.0~103.0% Standard: Enterprise Standard &n...
供应产品

Same products

Toilet Brush with Holder,Stainless Steel Toilet Brush
Toilet Brush with Holder,Stainless Steel Toilet Brush 卖方: Yonglian Tablewares Factory
Stainless Steel Bread Bin Storage Box, Roll up Lid (Stainless steel), Bread Bin, Bread Storage, Bread Holder
Stainless Steel Bread Bin Storage Box, Roll up Lid (Stainless steel), Bread Bin, Bread Storage, Bread Holder 卖方: Yonglian Tablewares Factory
Single Tear Paper Towel Holder, Brushed Stainless Steel Paper Towel Holder
Single Tear Paper Towel Holder, Brushed Stainless Steel Paper Towel Holder 卖方: Yonglian Tablewares Factory
Stainless Steel Colander for Kitchen Food Washing Self-Draining Pasta Bowl Wide Grip Handles
Stainless Steel Colander for Kitchen Food Washing Self-Draining Pasta Bowl Wide Grip Handles 卖方: Yonglian Tablewares Factory
Professional Quality Stainless Steel Mixing Bowl For Serving Mixing Cooking And Baking
Professional Quality Stainless Steel Mixing Bowl For Serving Mixing Cooking And Baking 卖方: Yonglian Tablewares Factory