Bivalirudin Trifluoroacetate
Product Name |
Bivalirudin Trifluoroacetate |
Sequence |
D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH |
Cas No. |
|
Molecular Formula |
C98H138N24O33 |
Molecular Weight |
2180.33 |
Purity (HPLC) |
98.0%min. |
Appearance |
White Powder |
Single Impurity (HPLC) |
1.0%max |
Amino Acid Composition |
±10% of theoretical |
Peptide Content (N%) |
≥80.0% |
Water Content (Karl Fischer) |
≤8.0% |
TrifluoroAcetate Content(HPIC) |
≤12.0% |
MS (ESI) |
Consistent |
Mass Balance |
95.0~105.0% |
2. Description:
Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a specific and reversible direct thrombin inhibitor (DTI).
Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.
Bivalirudin clinical studies demonstrated consistent positive outcomes in patients with stable angina, unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) undergoing PCI in 7 major randomized trials.
在线联系供应商
Other supplier products
Nandrolone laurate | Nandrolone laurate Chemical Name: 4-estren-17beta-ol-3-one laurate CAS NO.: 26490-31-3 Molecular Formula: C30H48O3 Molecular weight: 456.71 Appeara... | |
Deslorelin Acetate | Product Name Deslorelin Acetate Sequence Glp-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt Cas No. 57773-65-5 Molecular Formula C6... | |
Hormone Steroid Powder Methenolone Enanthate | Basic Info Model NO.:303-42-4 Alias:Primobolan Depot Type:Steroid Powder Powder:Hormone Specification:usp Methenolone Enanthate HS Code:2915900... | |
99% Purity Hot Sale Ananbolic Steroid Hormone Powder Trenbolone Acetate | Basic Info Model NO.:10161-34-9 Trenbolone Acetate CAS:10161-34-9 Trenbolone Acetate Mf:C20h24o3 Trenbolone Acetate Purity:99% Trenbolone Aceta... | |
99% Purity Steroid Powder Testosterone Enanthate for Bodybuilding | Basic Info Model NO.:315-37-7 Customized:Customized Suitable for:Adult Purity:>99% Alias:Primoteston Depot Testosterone Enanthate CAS:315-37-... |
Same products
共轨喷油器 | 卖方: 德艾普(厦门)进出口有限公司 | 商品名称:柴油喷油器型号: 最小起订量:1 件 材质:钢 包装详情:纸箱包装 库存:有库存 品牌:CNDIP 质保:6个月 | |
共轨喷油器 | 卖方: 德艾普(厦门)进出口有限公司 | 商品名称:柴油喷油器型号: 最小起订量:1 件 材质:钢 包装详情:纸箱包装 库存:有库存 品牌:CNDIP 质保:6个月 | |
共轨喷油器 | 卖方: 德艾普(厦门)进出口有限公司 | 商品名称:柴油喷油器型号: 最小起订量:1 件 材质:钢 包装详情:纸箱包装 库存:有库存 品牌:CNDIP 质保:6个月 | |
帕劳灌装液氮罐KGSQ液氮瓶 | 卖方: 河南天之道生物科技有限公司 | 在生命科学研究中,液氮是较为常用的冷冻介质,储存它的容器则成了重要实验工具。实验进行中,为了样本的低温储存环境稳定,需要定期补液以保证充足供应,因为液氮易挥发,液氮量随时间推推移而减少。因此,为... | |
Micronized Polyethylene Wax for Pigment Dispersant | 卖方: Syntop chemical Co.,Ltd. | Polypropylene wax is a chemical produced by pyrolysis, cut by heating and crushed by hot air It i... |