Sunifiram

Sunifiram
Quick Detail:
1.Place of Origin: China
2.CAS No.: 314728-85-3
3.EINECS: 219-034-4
4.Molecular Formula: C14H18N2O2
5.Assay: 99%
6.Molecular Weight: 246.30492
7.Appearance: Off-white to white crystalline powder.

Description:
Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric modulator of AMPA receptors, and has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, the best known being unifiram (DM-232).

This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation.
Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.



在线询价

至: Hubei Yuancheng Gongchaung Tech Co.,LTD
Your E-mail:
消息正文:


Send to other suppliers

Other supplier products

 Tylosin Phosphate
Tylosin Phosphate
 Halodrol Turinadiol steroid raw powder best supplier
Halodrol Turinadiol steroid raw powder best supplier
Oxfendazole  CAS 53716-50-0
Oxfendazole CAS 53716-50-0
Muscle Building Steroids Dehydronandrolone Acetate CAS 2590-41-2
Muscle Building Steroids Dehydronandrolone Acetate CAS 2590-41-2
Difloxacin hydrochloride
供应产品

Same products

Camera Rodder Pipeline and underwater video equipment
Camera Rodder Pipeline and underwater video equipment 卖方: Wan Qi electric power equipment factory
1756-OB16D	 1747-L541
1756-OB16D 1747-L541 卖方: MOORE (HK) AUTOMATION LIMITED
1770-KF2       1756-ENBT
1770-KF2 1756-ENBT 卖方: MOORE (HK) AUTOMATION LIMITED
1770-KF2       1756-ENBT
1770-KF2 1756-ENBT 卖方: MOORE (HK) AUTOMATION LIMITED
1756-L61         1756-L62
1756-L61 1756-L62 卖方: MOORE (HK) AUTOMATION LIMITED