Anastrozole
Product Name:Anastrozole
Synonyms:Arimidex;1-[3,5-Di-(1-Methyl-1-Cyano)-Ethyl]-Benzyl-1,2,4-Triazole;
Anastrozole;tetramethyl-5-(1h-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile;ZD-1033
CAS:
MF:C17H19N5
MW:293.37
Chemical properties:It can be crystallized from ethyl acetate-cyclohexane, the melting point is 81～82℃.
MP: 81-82°C
Storage Temp. :Store at RT
Usage:An aromatase inhibitor. Used as an antineoplastic.
Biological Activity:Potent and highly selective aromatase (CYP19) inhibitor (IC 50 = 15nM) that has no discernible effect on adrenocorticoid hormone synthesis. Reduces plasma estrogen levels and exhibits antitumor activity in vivo . Orally active.
Uses(1) It is the third-generation’s aromatase inhibitors, used for the treatment of advanced breast cancer of postmenopausal patients.
(2) Its used to cure the breast cancer.
(3) Anastrozole is the third-generation’s aromatase inhibitors, used for the treatment of advanced breast cancer of postmenopausal patients. It is an inhibitor for the triazole aromatase with a strong selectivity. It can inhibits aromatase which is prerequisite for the synthesis of pigment cells P-450 thereby blocking the biosynthesis of estrogens, and the estrogen is the essential part of the growth of breast cancer cells. Its used to cure the breast cancer, particularly suitable for postmenopausal women with advanced breast cancer who recrudescent after hormone adjuvant therapy.
在线联系供应商
Other supplier products
 |
17-Methyltestosterone | Product Name:17-Methyltestosterone Synonyms:Metandren;Mesterone;Methyltestosterone;4-Androsten-17alpha-Methyl-17beta-Ol-3-One;17alpha-Methyltestos... |
 |
甲基群勃龙 | Product Name:Methyltrienolone Synonyms:Metribolone;17b-Hydroxy-17-Methylestra-4,9,11-Trien-3-One; 17a-Methyl-Trenbolone;(17S)-17-Hydroxy-17-methy... |
 |
Testosterone Isocaproate | Product Name:Testosterone Isocaproate Synonyms:17beta-Hydroxyandrost-4-Ene-3-One 4-Methylvalerate;4-Androsten-17-Beta-Ol-3-One Isocaproate;4-Andro... |
 |
曲洛司坦 | Product Name:Trilostane Synonyms:(2-alpha,4-alpha,5-alpha,17-beta)-4,5-epoxy-17-hydroxy-3-oxoandrostane-2-car;17-beta)-ph;4-alpha,5-epoxy-17-beta-... |
 |
福美司坦 | Product Name:Formestane Synonyms:Lentaron;4-hydroxy-androst-4-ene-17-dione;4-hydroxy-delta(sub4)-androstenedione;4-Hydroxyandrost-4-Ene-3,17-Dione... |
Same products
 |
Peptide Technology Cooperation & Transfer | 卖方: PeptiOrigin Biotechnology Co., Ltd. | Peptide Technology Cooperation & Transfer Driving Innovation Through Strategic Partnerships ... |
 |
Recombinant Human Fibroblast Growth Factor-basic | 卖方: Hangzhou NeuroPeptide Biological Science and Technology Incorporation, Ltd | Physical Appearance:Freeze-dried powder Formulation:5mMPB(pH7.4) before freeze-drying TheorypI:... |
 |
Recombinant Staphylococcal Protein A | 卖方: Hangzhou NeuroPeptide Biological Science and Technology Incorporation, Ltd | TheorypI:5.10 Resources:Escherichia coli(E. coli) Purity:≥95% Storage condition:-20℃ Stora... |
 |
NuPerley Core 700 | 卖方: Hangzhou NeuroPeptide Biological Science and Technology Incorporation, Ltd | NuPerley Core 700 Matrix：Rigid agarose microsphere Ligand：n-octylamine Particle size, d50：~90 ... |
 |
Q NUPharose Fast Flow | 卖方: Hangzhou NeuroPeptide Biological Science and Technology Incorporation, Ltd | Matrix：6% Cross-linked agarose Ligand：Quaternary ammonium salt, -CH2CH(OH)CH2N(CH3)3+ Particle ... |
