.

他莫昔芬

Tamoxifen

Synonyms:(z)-2-(4-(1,2-diphenyl-1-butenyl)phenoxy)phenoxy)-n,n-dimethylethanamine;(z)-2-(para-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylamine;1-para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene;1-p-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene;n-dimethyl-2-(p-(1,2-diphenyl-1-butenyl)phenoxy)-(z)-ethylamin;Nolvadex-D

CAS:10540-29-1

MF:C26H29NO

MW:371.51

EINECS:234-118-0

Tamoxifen Chemical Properties

Chemical PropertiesWhite Crystalline Solid

Melting point 97-98 °C(lit.)

Water Solubility Insoluble in water. Soluble in methanol, ethanol, propanol or propylene glycol.Soluble in dimethyl sulfoxide, dichloromethane and ethanol. Insoluble in water.

Uses:Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response mo difiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.



在线联系供应商

至: Zhuhai Wumei Technology
Your E-mail:
消息正文:


Send to other suppliers

Other supplier products

美替诺龙庚酸酯
美替诺龙庚酸酯 Product Name:Methenolone Enanthate Synonyms:1(5-Alpha)-Androsten-1-Beta-Methyl-17-Beta-Ol-3-One Enanthate;[(5s,8r,9s,10s,13s,14s,17s)-1,10,13-Trim...
枸橼酸他莫昔芬
枸橼酸他莫昔芬 Product Name:Tamoxifen Citrate(Nolvadex ) Synonyms:1-p-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene citrate;(z)-2-(4-(1,2-diphenyl-1...
来曲唑
来曲唑 Product Name:Letrozole/ Femara Synonyms:4,4'-(1H-1,2,4-triazol-1-ylmethylene) bis-benzonitrile;femara;CGS-20267 CAS: MF:C17H11N5 MW:285.3 Chem...
十一酸诺龙
十一酸诺龙 Product Name:Nandrolone Undecylate Synonyms:Nandrolone Undecanoate;17beta-Hydroxyestr-4-En-3-One 17-Undecanoate; 17β-[(1-Oxoundecyl)Oxy]Estr...
他莫昔芬
他莫昔芬 Tamoxifen Synonyms:(z)-2-(4-(1,2-diphenyl-1-butenyl)phenoxy)phenoxy)-n,n-dimethylethanamine;(z)-2-(para-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimet...
供应产品

Same products

Food Grade CMC
Food Grade CMC 卖方: KIMA CHEMICAL CO.,LTD Food Grade CMC refers to a type of food additive known as sodium carboxymethyl cellulose, which i...
Ethyl Cellulose (EC) Wholesale
Ethyl Cellulose (EC) Wholesale 卖方: KIMA CHEMICAL CO.,LTD CAS9004 57 3 Ethyl Cellulose (EC), known as the ethyl ether of cellulose, is a cellulose deriv...
Textile Grade CMC
Textile Grade CMC 卖方: KIMA CHEMICAL CO.,LTD CMCtextile(Sodium Carboxymethyl Cellulose) is a type of cellulose derivative that is used in the ...
Paper-making Grade CMC
Paper-making Grade CMC 卖方: KIMA CHEMICAL CO.,LTD Paper-making grade CMC (Sodium Carboxymethyl Cellulose) is cellulose ether that is used in the pa...
Paint Grade CMC
Paint Grade CMC 卖方: KIMA CHEMICAL CO.,LTD CMCpaint(Sodium Carboxymethyl Cellulose) is a type of cellulose ether that is commonly used as a ...