Sweetening chrysanthemum P.E CAS No. : 91722-21-3

Melanotan-II


Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Molecular formula: C50H69N15O9
MW : 1024.180
CAS number: 121062-08-6
PubChem: 92432
MeSH: melanotan-II
Melanotan 2 Structural Name: Ac-cyclo[Nle4, Asp5, D-Phe7, Lys10]α-MSH4-10-NH2
Grade : Pharmaceutical Grade
Purity : 98%
Appearance : White Powder
Storage: Closed, below 2 ~ 8℃ preservation
Manufacturer : Hezhong
Usage : Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

Melanotan may refer to one of two separate peptides : Afamelanotide, originally developed under the names "Melanotan-1" or "Melanotan I" for skin tanning, a drug currently in trials in implant form as a prophylactic treatment for a series of light affected skin disorders and potential skin cancer preventative agent
Melanotan II, a drug originally developed as a skin tanning agent, but subsequently investigated as a potential treatment for sexual dysfunction
Melanotan 2 (also referred to as Melanotan II) is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis, a process responsible for pigmentation of the skin. This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.
Additionally, Melanotan 2 and a similar synthetically produced variant, known as PT-141, have been studied at length as a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.

A few synthetic analogues of α-MSH have been investigated for their apparent photoprotective effects against ultraviolet (UV) radiation from the sun, namely Melanotan (afamelanotide) and Melanotan II, referred to as Melanotan 2. Bremelanotide, another analogue of α-MSH similar to Melanotan 2, is currently under development for the treatment of sexual dysfunction. All of these melanotan peptides have significantly greater potencies than α-MSH, but with distinctive selectivity peptide profiles.


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