Recombinant human Interleukin-18-binding protein

Product Name:
Recombinant human Interleukin-18-binding protein
Product Type : Recombinant Protein
Code : CSB-RP167394h
Size : 1mg
Uniprot NO. : O95998
Research Area : Immunology
Source : E.coli
Gene Names : IL18BP
Expression Region : 31-183aa
Product Info : His-tag
Mol. Weight : 20.6kD
Protein Description : Partial of the full length of 31-194aa
Target details : This protein is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn s disease. Alternative splicing results in multiple transcript variants.

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