Rat C4b-binding protein beta chain(C4BPB) ELISA kit

Product Name:
Rat C4b-binding protein beta chain(C4BPB) ELISA kit
Product Type : ELISA Kit
Code : CSB-EL003954RA
Size : 96T,5×96T,10×96T
Uniprot NO. : Q63515
Abbreviation : C4BPB
Protein Biological Process 1 : Complement
Alias : C4BP, C4b binding protein, beta chain|complement component 4 binding protein, beta chain|complement component 4-binding protein, beta
Species : Rat
Protein Biological Process 3 : Complement pathway
Detect Range : Request Information
Sensitivity : Request Information
Assay Time : 1-5h
Sample Volume : 50-100ul
Detection Wavelengt : 450 nm
Availability : 5-7 working days
Research Area : Immunology
Target details : This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.

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