Human Serine/threonine-protein kinase B-raf(BRAF) ELISA kit

Product Name:     
Human Serine/threonine-protein kinase B-raf(BRAF) ELISA kit
Product Type :     ELISA Kit
Code :     CSB-EL002791HU
Size :     96T,5×96T,10×96T
Uniprot NO. :     P15056
Abbreviation :     BRAF
Alias :     B-RAF1, BRAF1, FLJ95109, MGC126806, MGC138284, RAFB1, 94 kDa B-raf protein|B-Raf|B-Raf proto-oncogene serine/threonine-protein kinase (p94)|murine sarcoma viral (v-raf) oncogene homolog B1
Species :     Human
Sample Types :     serum, plasma, cell lysates
Detect Range :     31.25 pg/ml-2000 pg/ml
Sensitivity :     7.8pg/ml
Assay Time :     1-5h
Sample Volume :     50-100ul
Detection Wavelengt :     450 nm
Availability :     7-14 working days
Research Area :     Cell Biology
Protocol :     
 Instructions
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Target details :     This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

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