Muscular Relaxant White to Very Faintly Yellow Solid Baclofen 99%

 
Quick Detail:
Baclofen
Purity: 99.0% (HPLC)
CAS Number: 1134-47-0
Molecular Formula: C10H12ClNO2
Molecular Weight: 213.68
EINECS: 214-486-9
Appearance: White to very faintly yellow solid

Description:
Baclofen (brand names Kemstro, Lioresal, Liofen, Gablofen, Lyflex, Beklo and Baclosan) is a derivative of gamma-aminobutyric acid (GABA). It is primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant.

It is an agonist for the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. Baclofen can also be used to treat hiccups.

A beneficial property of baclofen is that tolerance does not seem to occur to a significant degree - Baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some patients receiving intrathecal baclofen treatment.

Applications:
It is skeletal muscular relaxant. It is use to improve spasm symptom of muscular hypertonia caused by pyramidal tract damage, spastic hemiplegia and paraplegics caused by deferent cause, such as multiple sclerosis, cerebrovascular disease, spinal cord injury and so on; Improve Duchenne patient s repeated vomiting caused by duodenal obstruction, relieve prosopalgia and postherpetic neuralgia; Improve parkinson disease, tardive dyskinesia and Huntington desease.

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