Heparin Sodium
CAS No.:9041-08-1MF:(C12H16NS2Na3)20Appearance:White PowderSpecifications1. Product: Heparin sodium 2. Speicfication: EP 7.0, USP 34 3. Reasonable price 4. Good serviceSpecificationTestAcceptance criteriaOriginPorcine intestinal mucosaAppearanceWhite or almost white, hygroscopic powderSolubilityFreely soluble in waterIdentificationA:delays the clotting of sheep plasma B:1H-NMR: complies with EP 7.0 specification of heparin sodium about 1H-NMR requirements C:Chromatographic identity: the retention time and the shape of the principal peak from the sample solution are similar to that from the standard solution D:complies with the test for sodiumAppearance of solutionClear and not more intensely colored than intensity 5 of reference solutionpH5.5~8.0Nitrogen1.5%~2.5%Sodium9.5%~12.5%Nucleotide impurities260nm: not greater than 0.15ProteinNot more than 0.5%Related substancesDermatan sulfate: Not more than 2.0% Total impurities: Not more than 3.0%GalactosamineNot more than 1.0%Heavy metalsNot more than 20 ppmLoss on dryingNot more than 8.0%Bacterial endotoxinsLess than 0.01 IU/heparin IUPotencyAt least 180 IU/mg
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