17alpha-Oestradiol

17alpha-Oestradiol

Synonyms: epiestradial;

CAS: 57-91-0

EINECS: 200-023-8

Assay: 98% min.

Standard: USP34

Packing: foil bag or tin.

Delivery: Express courier.

MF: C18H24O2

MW: 272.38

Character: White Solid. Mp 176-180℃. solubility  ethanol: 50 mg/mL, clear, colorless

Usage: Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke.

Biological Activity Endogenous estrogen receptor ligand

 . Application:

Alfatradiol is used in form of an ethanolic solution for topical application on the scalp. Similarly to other drugs against alopecia, topical or oral, it has to be applied continuously to prevent further hair loss. Regrowth of hair that was already lost is only possible to a limited extent. In general, advanced alopecia does not respond well to medical treatment, which has historically been thought to be a consequence of the hair roots being lost.
A university-led study (including several authors who are advisors to companies) in 103 women comparing alfatradiol to minoxidil, another topical hair loss treatment, found the latter to be more effective. In contrast to minoxidil, alfatradiol did not result in an increase of hair density or thickness, but only in slowing down or stabilization of hair loss in this study. In an earlier study, no systemic side effects were noted, and 17α -estradiol was found to reduce androgenic hair loss, though it was not effective at growing new hair.


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Packaging Details 1kg/foil bag or as required
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Supply Ability: Mass stock



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