Female Steroid Powder Ethinylestradiol 57-63-6

Ethinylestradiol
Synonyms: NOVESTROL; NEO-ESTRONE; ETHYNYLESTRADIOL
CAS NO: 57-63-6
Molecular Weight: 296.41
Molecular Formula: C20H24O2
Appearance: Off-White to Light-Yellow Crystalline Powder
Storage: In cool & dry place, keep away from strong light.
Export Markets:Global
Packing: Discreet Packing ways for your choice.
Usage: A synthetic steroid with high oral estrogenic potency
Standard: USP28

Ethinyl Estradiol is absorbed in the small intestine and reaches a serum peak about 2 hours later. It undergoes extensive metabolism in the liver involving the cytochrome P450 3A4 isoenzyme.

Ethinyl Estradiol and its metabolites are excreted with the bile. Due to the effect of entero hepatic circulation a second peak is seen several hours later. Individually, wide variations exist in the overall absorption process, and can be further modified by drugs that affect the enterohepatic circulation or liver enzymes.

In circulation Ethinyl Estradiol is almost fully bound to plasma albumin. It is metabolized by hydroxylation of the aromatic ring and excreted in both feces and urine, in part as glucuronide and sulfate conjugate.

Ethinyl Estradiol is hormonally effective by activating the estrogen receptor and thus is an estrogen. It finds its most common use in the estrogen-progestin combination preparations of oral contraceptives. Over time, formulations have decreased the Ethinyl Estradiol dose from as high as 100 μg to as low as 10 μg



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