Glucocorticoid Steroids Budesonide CAS 51333-22-3 for Antineoplastic

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Glucocorticoid Steroids Budesonide CAS 51333-22-3 for Antineoplastic

Budesonide
Synonyms: PREFERID;PULMICORT;SPIROCORT;S-1320;RHINOCORT;BIDIEN;BUDESONIDE;CORTIVENT
CAS: 51333-22-3
MF: C25H34O6
MW: 430.53
EINECS: 257-139-7
Chemical Properties White Solid
Usage A non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent
Usage laxative, antineoplastic
Biological Activity Synthetic anti-inflammatory glucocorticoid that displays chemopreventive activity. Prevents formation of lung adenomas and adenocarcinomas in mice following inhalation or oral administration. Reverses DNA hypomethylation and modulates expression of cancer related genes.

Budesonide Attribute:
Budesonide is a glucocorticoid steroid for the treatment of asthma, COPD and non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis. In addition, it is used for inflammatory bowel disease. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Budesonide Effect:
Budesonide is nebulized for maintenance and prophylactic treatment of asthma. also for treatment and prevention of nasal polyposis. maintenance of remission (for up to 3 months) of Crohn's disease (mild-to-moderate) involving the ileum and/or ascending colon. Budesonide assists in the induction of remission in patients with active ulcerative colitis.

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