Glucocorticoid Steroids Mometasone Furoate CAS 83919-23-7 for Anti-inflammatory



Glucocorticoid Steroids Mometasone Furoate CAS 83919-23-7 for Anti-inflammatory

Mometasone furoate
Synonyms: SCH-32088;MOMETASONE 17-FUROATE;MOMETASONE FUROATE;NASONEX;(11-beta,16-alpha)-xy-16-methyl;pregna-1,4-diene-3,20-dione,9,21-dichloro-17-((2-furanylcarbonyl)oxy)-11-hydro;9-chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one furoate;(11BETA,16ALPHA)-9,21-DICHLORO-17-[(2-FURANYLCARBONYL)OXY]-11-HYDROXY-16-METHYLPREGNA-1,4-DIENE-3,20-DIONE
CAS: 83919-23-7
MF: C32H32Cl2O8
MW: 615.5
Chemical Properties White-to-Off-White Solid
Usage A topical corticosteroid used as an anti-inflammatory

Mometasone Furoate Application:

Mometasone furoate is used in the treatment of inflammatory skin disorders (such as eczema and psoriasis), allergic rhinitis(such as hay fever), asthma for patients unresponsive to less potent corticosteroids, and penile phimosis. In terms of steroid strength, it is more potent than hydrocortisone, and less potent than dexamethasone.

Mometasone is indicated for the alleviation of inflammatory and pruritic manifestations (with stinging and itching) of dermatosis which respond to treatment with glucocorticoides such as psoriasis and atopic dermatitis (affection dermic chronic, characterized by the apparition of squamous eruptions, accompanied by itching).
Nasal mometasone is employed in adults (including the elderly) and children of the age greater or equal to 2 years for diminishing the symptoms which may present themselves as hayfever (seasonal allergic rhinitis) or other allergies which present during longer parts of the year (perennial rhinitis), including nasal obstruction (congestion), nasal discharge, pruritus and sneezing.To help prevent these symptoms, this drug can be used two to four weeks before the anticipated of the pollen season. Mometasone is also indicated for the treatment of nasal polyps (small formations in the mucosa of the nose) and symptoms associated with including congestion and hyposmia in adult patients over the age of 18. The principal symptom is the sensation of nasal obstruction. It can also produce nasal drip, sensation of tickling in the throat and loss of the sense of taste and smell.

Mometasone Furoate Specification:

Test Item Standard Test Result
Appearance white crystal or powder white crystal or powder
Identification infra-red spectrum accord with normal frequency spectrum
Specific rotation +56¡ãC-+62¡ãC +60.56¡ãC
Drying Loss ¡Ü0.5% 0.27%
Residue on Ignition ¡Ü0.1% 0.08%
Heavy metal ¡Ü30ppm 18ppm
Assay 97.0%-103.0% 98.2%

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