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Oral & Injectable Progestogen for Gynaecological Conditions Dydrogesterone CAS 152-62-5

  

  1. Quick Detail:

 

Product Name

Dydrogesterone

Alias

terolut; dufaston; gynorest; diphaston; duvaron

CAS

152-62-5

EINECS

205-806-8

Assay

 

Appearance

white to off-white crystalline powder

Molecular Formula

C21H28O2

Molecular Weight

 

Grade

Pharmaceutical Grade

 

Description:

 

Dydrogesterone is a steroidal, pure progestin that was developed in the 1950s. Dydrogesterone has selective progestational activity and does not inhibit ovulation. The greater rigidity of dydrogesterone also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of dydrogesterone is 10–20 times lower than that of oral micronized progesterone.

 

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