Pharmaceutical materials

Isotretinoin / Accutane for Treatment of Severe Acne 4759-48-2 

Isotretinoin (Accutane) is primarily used to treat bad cases of cystic acne, and to help the skin more rapidly renew itself. In addition, it is used in rare cases for certain skin cancers and skin diseases. It is a type of retinoid, which is naturally found in the body in small amounts. 
Name: Isotretinoin 

Basic info 
Synonym: 13-cis-ra;13-cis-retinoicaci;13-ra;accutane;Isoretinoin;isotrex;neovitaminaacid;ro-4-3780 
CAS: 4759-48-2 
MF: C20H28O2 
MW: 300.44 
EINECS: 225-296-0 
Assay: 99% 
Chemical Properties: Yellow-Orange Crystalline Powder 
Usage: Used as a treatment for severe acne. Presently being studied in conjuction with the treatment of photoaged skin. 
Usage: 5HT1a receptor agonist, anxiolytic 
Package: 100g/foil bag 

Accutane works as an isomer of Vitamin A, which reduces the amount of oil released by the oil glands in the skin; this will make it difficult for acne to form and reduce it significantly. Nearly all patients achieve clearing of acne during a course, with 90% reporting'excellent' results with higher dosages. 

Bodybuilders who use anabolic steroids have utilized accutane to counteract the negative effects of steroids on their skin; especially, the acne related side effects. 
Since chances of acne are increased with anabolic steroid use, and bodybuilding requires looking good (especially physique competitors), many athletes who have failed to conquer their acne with natural remedies will turn to accutane. 
It is the androgenic increases associated with steroids that will trigger increased acne. This is especially true for those genetically prone to the condition. Also, the hormonal changes can trigger acne as well, such as increased testosterone levels. 

Accutane Dosage 
Among bodybuilders, the dosage should be conservative. Once a day dose of 10-20mgs for 6-8 weeks maximum should work fine. Among the general public fighting acne, a dosage of 50-150mg per day may be prescribed by their physician. It is a good idea to take the drug with a large meal. In addition, it may be necessary to use multiple courses of treatment
CAS No.: 104987-11-3
Purity: 99.5%
MF: C44H69NO12
MW: 804.02
Density: 1.19 g/cm3
Melting Point: 113-115° C
Boiling Point: 871.7 ° C at 760 mmHg
Vapour: 1.73E-35mmHg at 25° C
Refractive Index: 1.549
Flash Point: 481 ° C

Additional information

Payment terms Western union , Money gram, Bank transfer , Bitcoin
Min order quantity 10grams
Delivery Sent out within 12 hours after payment confirmed
Lead time 4-7 days
Packaging Disguised package or as required
Origin China
Shipping Express Courier(EMS,DHL,UPS,TNT,FedEX)

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heart liver kidney and bone marrow transplant patients preferred immune-suppressing drugs after the transplant rejection resistant to conventional immunosuppressive regimen, is also the choice of the drug... Adverse reactions similar to cyclosporine. autoimmune eye disease and other autoimmune diseases also play an active role.


It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation. Long term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate and IL-2 receptor inhibitors. Dosages are titrated to target blood levels. Typical starting doses for once daily tacrolimus are 0.15-0.20 mg/kg body weight


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