Pharmaceutical materials

Bimatoprost Reduce Iop prostaglandin hormone treatment CAS 155206-00-1

Synonyms: N-ETHYL-9ALPHA,11ALPHA,15S-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z, 13E-DIEN-1-AMIDE;BIMATOPROST;BIMATOPROST(TM);17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ETHYL AMIDE;BIMATOPROST;17-phenyl-tri-norprostaglandin f2α-ethyl amide;(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide
CAS: 155206-00-1
MF: C25H37NO4
MW: 415.57
Product Categories: Prostaglandins;Prostaglandin;Chiral Reagents;Pharmaceuticals;Lipids in Cell Signaling
Chemical Properties Crystalline Solid
Assay 99%
Usage Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes.
Packing foil bag or as required

Function : Used in patients with primary open-angle glaucoma, or other effects in drug use is invalid after repeated measurement (not to the expected level of intraocular pressure) or intolerance to the patients with elevated intraocular pressure.It is considered to be the strongest local IOP reduction glaucoma medications, for normal people and patients with POAG and OHT, mainly used for drug intolerance to other IOP reduction or use other IOP reduction drugs ineffective in patients with POAG or OHT.

2.Bimatoprost COA:
Appearance White to yellow crystalline powder White crystalline powder
Identification A. Should meet the requirement Conforms
B. Should meet the requirement Conforms
Impurity A ≤0.5% N.D.
Impurity B ≤0.3% 0.075%
Loss on drying ≤0.5% 0.085%
Residue on Ignition ≤0.1% 0.045%
Residual solvent Ethanol≤0.5% 0.026%
Ethyl acetate≤0.5% N.D.
Tetrahydrofuran≤0.072% N.D.
Heavy Metal ≤20ppm Conforms
Assay 98.0%~102.0% (Calculated on the dried basis) 99.66%


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