99.5% Purity USP Female Steroidal Progestin Hormone Megestrol Acetate CAS 595-33-5
99.5% Purity USP Female Steroidal Progestin Hormone Megestrol Acetate CAS 595-33-5
Basic Info.
Product Name: Megestrol acetate
CAS: 595-33-5
MF: C24H32O4
MW: 384.51
EINECS: 209-864-5
mp: 214°C
refractive index: 11°(C=2, CHCl3)
Chemical Properties:Crystalline Solid
Usage:Progestogen;Progesterone receptor agonist,Orally active progestogen; formerly used in combinations as oral contraceptive,treatment of endometrial hyperplasia
Description:
Megestrol acetate is used mainly as an appetite stimulant in a variety of conditions and as an antineoplastic agent in the treatment of breast, endometrial, and prostate cancers.
When given in relatively high doses, it can substantially increase appetite in most individuals, even those with advanced cancer, and is often used to boost appetite and induce weight gain in patients with cancer or HIV/AIDS-associated cachexia. It is also used as a contraceptive in combination with an estrogen at relatively low doses.
Application:
Megestrol acetate is used mainly as an appetite stimulant in a variety of conditions and as an antineoplastic agent in the treatment of breast, endometrial, and prostate cancers. When given in relatively high doses, it can substantially increase appetite in most individuals, even those with advanced cancer, and is often used to boost appetite and induce weight gain in patients with cancer or HIV/AIDS-associated cachexia. It is also used as a contraceptive in combination with an estrogen at relatively low doses.
In addition to its use in humans, megestrol acetate has been used extensively in veterinary medicine in the treatment of medical conditions in cats and dogs.
Usage:
Megestrol acetate is available as 5 mg, 20 mg and 40 mg tablets and in oral suspensions of 125 mg/ml and 40 mg/ml. It is used at a dose of 5 mg in combination with an estrogen for contraception. Appetite stimulation is achieved with doses ranging from 400 mg to 800 mg a day. Doses used to treat cancer usually range from 40 mg to 320 mg.
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