TB-500, 2mg/vial

 Synonyms: S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide;N-[4-Nitro-3-(trifluoromethyl)phenyl]-(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methylpropanamide;Ostarine;(2R)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluorome

CAS:401900-40-1

MF:C19H18F3N3O6
MW:441.36
MP:70-74°C
Density:1.47
Purity 99%

USAGE:
1.Andarine (S-4) is an investigational selective androgen receptor modulator (SARM) for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy,using the non-steroidal androgen antagonist bicalutamide as a lead compound.
2.Andarine is an orally active partial agonist for androgen receptors. It is less potent in both anabolic and androgenic effects than other SARMs. In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects.
3.This suggests that it is able to competitively block binding of dihydrotestosterone to its receptor targets in the prostate gland, but its partial agonist effects at androgen receptors prevent the side effects associated with the anti-androgenic drugs traditionally used for treatment of BPH.
4.Clinical development of Andarine has been abandoned, given in humans it results in a series specific toxic metabolite.



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