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Tamoxifen Citrate

Chemical Name: (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxyl]-N,N-dimethyl-ethanamine-citrate;
1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene citrate

Molecular Formula: C26H29NO.C6H8O7

Molecular weight: 563.64

CAS NO.: 54965-24-1

Appearance: white crystalline powder ; MP: 140-144 ºC

Usage:anti-estrogen, protein kinase C inhibitor, beneficial cardiovascular effects, bone cancer treatment, induces DNA adduct formation

Biological Activity:Estrogen receptor antagonist/partial agonist. Selective and potent inhibitor of mammalian sterol isomerase. Neuroprotective in female rats in vivo . Also high affinity agonist at the membrane estrogen receptor GPR30.

Standard: CP/2000; USP/26




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