Dapoxetine Hydrochloride

Dapoxetine Hydrochloride

Synonyms: d-Dapoxetine hydrochloride; DL-Dapoxetine hydrochloride

CAS: 129938-20-1
Assay: 98% min.
Packing: 1kg net/foil bag or tin.
Delivery: Express courier.
MF: C9H7ClN2O5
MW: 258.62
Purity: 99%
For more details Plz contact: lmy@ycphar.com
Skype:miss.littlemegan

Character: White to Off-White Cyrstalline Solid, odorless, slight sweet taste, Mp 175-177°C, optical rotation +128°
Usage: Selective serotonin reuptake inhibitor (SSRI), pharmaceutical material, hormone.
Description:

Dapoxetine (dapoxetine) as a new fast SSRI, a short half life, a selective 5 - HT reuptake inhibitor (SSRI), for the treatment of premature ejaculation and erectile dysfunction. Dapoxetine is a selective 5 - HT reuptake inhibitor (SSRI), such drugs widely used to treat depression and related affective disorders

Applications:

Treat male premature ejaculation and erectile dysfunction.
Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as
fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE.
Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two
to ninefold above base line in comparison of three to eightfold when dapoxetine is used. However, these SSRIs
must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug
accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing
erectile dysfunction. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated
from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's
accumulation in the body, and therefore reducing side effects.



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