H3S10PH
Synthesized histone H3 peptide corresponding to residues within 1-135 of human histone H3 with phosphorylation S10 modification.
SPECIFICATION OF H3S10PH
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CAT |
H3301 |
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Product Name |
HistoneH3-S10ph |
|
Purity |
≥95% by HPLC analysis |
|
Appearance |
White powder |
|
Usage |
Research use only |
|
Storage |
Shipping at room temperature. Upon delivery aliquot. Stored at -20°C or -80°C. Avoid freeze/thaw cycle. |
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Sequence |
ARTKQTARKS(ph) TGGKAPRKQL ATKAARKSAP ATGGVKKPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA |
APPLICATION OF H3S10PH
Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function. H3S10ph is important for chromosome condensation and cytokinesis during mitosis in mammals. H3S10ph is emerging as an important player in the initiation and propagation of cancer, as it facilitates cellular malignant transformation and participates in fundamental cellular functions.
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