Thyroid Peroxidase (TPO)
Thy peroxidase(TPO), also called thyroperoxidase or thyroid peroxidase igg, catalyzes the iodization of thyroglobulin tyrosine during the biosynthesis of T3 and T4.
TPO is an enzyme expressed mainly in the thyroid, where it is secret into the colloid.
The increased TPO level may reflect the promoted thyroid hormone synthesis, which may cause hyperthyroidism.
The detection of TPO helps with diagnosing Hashimoto's disease (HD) and autoimmune hyperthyroidism; Toxic chronic goiter (Graves); Monitoring the effect of immunotherapy; To detect the possibility of familial thyroid disease; Prediction of postpartum thyroid dysfunction in pregnant women.
SEKBIO provides Humanised anti-human TPO mAb for diagnosis usage.
Types Of Thyroid Peroxidase (TPO)
|
Name |
|
Humanized Anti-human TPO mAb |
Thyroid Peroxidase Intro
Thyroid peroxidase(TPO) TPO is an important enzyme that catalyzes thyroid hormones. TPO is synthesized by thyroid follicular cells. It is a 10% glycated hemoglobin-like protein composed of 933 amino acid residues with a molecular weight of 103 kD. It is most abundantly distributed in the microvilli on the follicular lumen surface. TPO uses hydrogen peroxide as an oxidant. TSH regulates the generation and activity of TPO. In the experiment, the action of TPO disappeared 48 hours after removing the rat pituitary, and TPO activity will restore after the injection of thyroid-stimulating hormone. Thiourea drugs can inhibit the activity of TPO, thus inhibiting the synthesis of thyroid hormones, and are commonly used clinically for the treatment of hyperthyroidism (hyperthyroidism).
Thyroid Peroxidase Antibody
Thyroid peroxidase (TPO) is a membrane-bound heme protein with a molecular weight of about 100,000. TPO participates in two different reactions in the biosynthesis of thyroid hormones. If thyroid peroxidase antibodies are present, it is a sign of concomitant damage to thyroid function or potential harm. Peroxidase antibody-positive suggests that the thyroid disease may be Hashimoto's thyroiditis.
Sekbioprovide thyroid antibodies tpo and tg, high tpo and tg antibodies, ivd antibodyand etc. want to anti thyroid peroxidase antibody test costor more, contact us.
Send product request
Other supplier products
 |
Mouse Anti-human ProGRP mAb | Pprogrp antibody Name: Mouse anti-human ProGRP mAb Catalog No.: ZLA116-1M Description: Mouse mAb Epitope: 48-52 As a professional tumor marker... |
 |
Triiodothyronine (T3) | Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and developme... |
 |
Inflammatory Marker | Inflammatory cytokines refer to various cytokines involved in the inflammatory response. And the inflammatory markers can identify the severity and... |
 |
Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA II Tumor Marker) | In the absence of vitamin K, liver cells cannot depend on vitamin K in the synthesis of standard clotting factors, only the synthesis of no functio... |
 |
25-OH Vitamin D | Vitamin D is converted to 25-hydroxyvitamin D (25-OH-VD) by hydroxylation in the liver and the active 1, 25-dihydroxy vitamin D in the kidneys. ... |
