Steroidal Progestin CAS 595-33-5 Megestrol Acetate (MGA)
Steroidal Progestin CAS 595-33-5 Megestrol Acetate (MGA)
1.Quick Detail:
Megestrol acetate
Megestrol acetate Product Name:Megestrol acetate
Megestrol acetate CAS:595-33-5
Megestrol acetate MF:C24H32O4
MW:384.51
EINECS:209-864-5
mp:214°C
Megestrol acetate refractive index:11°(C=2, CHCl3)
Megestrol acetate Chemical Properties:Crystalline Solid
Megestrol acetate Usage:Progestogen;Progesterone receptor agonist,Orally active progestogen; formerly used in combinations as oral contraceptive,treatment of endometrial hyperplasia
2.Description:
Megestrol acetate (INN, USAN, BAN, JAN) (abbreviated as MGA or MA, and sold mainly under the brand names Megace and Megace ES), also known as 17α-acetoxy-6-dehydro-6-methylprogesterone, is a steroidal progestin and progesteronederivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropiceffects.
Though sometimes referred to simply as megestrol, it is important to clarify that megestrol acetate is not the same asmegestrol, which is a closely related but different compound.
3. Application:
Megestrol acetate is used mainly as an appetite stimulant in a variety of conditions and as an antineoplastic agent in the treatment of breast, endometrial, and prostate cancers. When given in relatively high doses, it can substantially increase appetite in most individuals, even those with advanced cancer, and is often used to boost appetite and induceweight gain in patients with cancer or HIV/AIDS-associated cachexia. It is also used as a contraceptive in combination with an estrogen at relatively low doses.
In addition to its use in humans, megestrol acetate has been used extensively in veterinary medicine in the treatment of medical conditions in cats and dogs.
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Storage
Store in cool and dry area and keep away from direct sunlight.oC
Shelf life
2 years, keep in formal storage condition.
MOQ
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