Dexamethasone Palmitate

Dexamethasone Palmitate

Synonyms: Dexamethasone-21-palmitate

CAS: 14899-36-6

Molecular formula: C38H59FO6

MW: 630.87

Packing: 5KG/TIN,2TIN/CTN

Unit: KG

Chemical Properties: Colourless Thick Oil

Usage: A corticosteroid prodrug for the treatment of eye disorders.

Abstract
PURPOSE:
Dexamethasone palmitate (DXP) is a lipophilic prodrug of dexamethasone (DXM), a potent corticosteroide used to treat a variety of ophthalmic diseases. The aim of the study was to characterize the sustained release capacity (in rabbit), efficacy (in rat and rabbit), and safety (in rabbit, cat, and minipig) of intravitreal (IVT) DXP emulsions in preclinical models.