White Crystalline Powder Pharmaceutical Intermediates Trilostane Cas 13647-35-3
White Crystalline Powder Pharmaceutical Intermediates Trilostane Cas 13647-35-3
Basic Info.
Trilostane
Synonym: Vetoryl
CAS : 13647-35-3
Molecular Formula: C20H27NO3
Molecular Weight: 329.4333
Assay :99%
Einecs No: 237-133-0
Grade : Pharmaceutical Grade
Storage: Shading, confined preservation
Appearance:: White crystalline powder
Usage : Trilostane can inhibit cortical hormone in the process of synthesis of 3 beta dehydrogenase, make the cortisol, aldosterone synthesis decreased, clinically used in the treatment of Cushing syndrome (hypercortisolism) and primary aldosteronism. This product also had significantly effect to decreased serum testosterone level.
Product Description:
Trilostane is used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible. Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.
Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxysteroid dehydrogenase/delta 5,4 ketosteroid isomerase, thus blocking synthesis of adrenal steroids.
Side effect:Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting.
Application:
Trilostane can suppress cortical hormone synthesis process of 3 beta dehydrogenase, make cortisol, aldosterone synthesis reduce, clinical used in the treatment of Cushing syndrome(cortisol increase disease) and primary aldosteronism,the effect is not good than testosterone metyrapone. This product has significantly reduced blood testosterone level role, may relevant to its inhibit synthetic.
Отправить запрос, связаться с поставщиком
Другие товары поставщика
 |
Steroid Medical Tools Solution 99.5% High Purity Test Blend 450 mg / ml For Muscle Building | Steroid Medical Tools Solution 99.5% High Purity Test Blend 450 mg / ml For Muscle Building Basic Info: Test Blend 500 each 1ml contains: 200 mg... |
 |
Pharmaceutical Raw Material for Vitamin C Ascorbic Acid CAS 50-81-7 | Pharmaceutical Raw Material for Vitamin C Ascorbic Acid CAS 50-81-7 Basic Info. Product Name: Vitamin C Synonyms: L-Ascorbic Acid, Free Acid; V... |
 |
99.9% Pramoxine Hydrochloride Anesthetic Anodye CAS 637-58-1 Pramoxine HCl | 99.9% Pramoxine Hydrochloride Anesthetic Anodye CAS 637-58-1 Pramoxine HCl Basic Info. English name: Pramoxine Hydrochloride CAS: 637-58-1 EINE... |
 |
Pharmaceutical Raw Materials Diclofenac Sodium for Antipyretic Analgesics | Pharmaceutical Raw Materials Diclofenac Sodium for Antipyretic Analgesics Basic info: Diclofenac sodium Synonyms: diclophenacsodium;gp45840;huma... |
 |
High Quality Pharmaceutical Raw Material Conform USP Diethylstilbestrol | High Quality Pharmaceutical Raw Material Conform USP Diethylstilbestrol Basic Info. Diethylstilbestrol Alias:stilbestrol Synonyms: DES;3,4-Bis(... |
