99% High Purity Articaine Hydrochloride/Articaine HCl 23964-57-0
99% High Purity Articaine Hydrochloride/Articaine HCl 23964-57-0
Basic Info.
CAS No.: 23964-57-0
Packing: 25kg/drum
M.F.: C13H21ClN2O3S
M.W.: 320.8354
Appearance: White crystalline powder
Model NO.:23964-57-0
Assay:99.5%
CAS:23964-57-0
Grade Standard:USP/BP
Market:Global
Description:
Articaine hydrochloride, its CAS NO. is 23964-57-0, the synonyms are 2-Thiophenecarboxylic acid,4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-, methyl ester, monohydrochloride ; 4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic acid methyl ester HCl ; Articaine HCl ; Methyl4-methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylate, monohydrochloride ; Septanest ; Septocaine. Articaine is a dental local anesthetic. It is the most widely used local anesthetic in a number of European countries and is available in many countries around the world.
Application:
Structure and Metabolism
The amide structure of articaine is similar to that of other local anesthetics, but its molecular structure differs through the presence of a thiophene ring instead of a benzene ring. Articaine is exceptional because it contains an additional ester group that is metabolized by esterases in blood and tissue. The elimination of articaine is exponential with a half-life of 20 minutes. Since articaine is hydrolized very quickly in the blood, the risk of systemic intoxication seems to be lower than with other anesthetics, especially if repeated injection is performed.
Articaine is a local anaesthetic that has been approved overseas for several years. Like other amide anaesthetics, articaine blocks nerve conduction when it is infiltrated around a nerve. This action is prolonged by combining the drug with a vasoconstrictor such as adrenaline.
The combination of articaine and adrenaline can be used for local or regional anaesthesia for dental procedures. Anaesthesia begins within six minutes and lasts for an hour. The half-life of articaine is approximately 1.8 hours. It is metabolised and then mainly excreted in the urine.
Clinical use
(1) Articaine is used for pain control. Like other local anesthetic drugs, articaine causes a transient
and completely reversible state of anesthesia (loss of sensation) during (dental) procedures.
(2) In dentistry, articaine is used both for infiltration and block injections, with the block technique
yielding the greatest duration of anesthesia.
(3) In people with hypokalemic sensory overstimulation, lidocaine is not very effective, but articaine
works well.
Отправить запрос, связаться с поставщиком
Другие товары поставщика
 |
Polysorbate 80 Safe Organic Solvents for Used in food Emulsifier 9005-70-3 | Polysorbate 80 Safe Organic Solvents for Used in food Emulsifier 9005-70-3 Basic Info. Basic info: Tween 85 CAS:9005-70-3 MF:C24H44O6 MW:428.... |
 |
High Quality Factory Direct Supply Estrogen Hormone Estradiol Enanthate | High Quality Factory Direct Supply Estrogen Hormone Estradiol Enanthate Basic Info. CAS Number: 4956-37-0 Purity: 99% Molecular Weight: 384.556 ... |
 |
Factory Supply 99.9% Purity Polyethylene Glycol/PEG CAS 25322-68-3 | Factory Supply 99.9% Purity Polyethylene Glycol/PEG CAS 25322-68-3 Basic Info. Poly(ethylene glycol) Synonym:Glycols,polyethylene (8CI);AlkoxE ... |
 |
Anabolic Steroids Raw Stenbolone Powder 5197-58-0 Methylstenbolone for Muscle Growth | Anabolic Steroids Raw Stenbolone Powder 5197-58-0 Methylstenbolone for Muscle Growth Basic Info. Methylstenbolone (stenbolon; Stenebolone; methy... |
 |
99% High Purity Local Anesthetic Tetracaine Hydrochloride/Tetracaine HCL | 99% High Purity Local Anesthetic Tetracaine Hydrochloride/Tetracaine HCL Basic Info. Product Name: Tetracaine hydrochloride Synonyms: Tetracain... |
