Pharmaceutical Raw Materials Cabergoline 81409-90-7 Used To Parkinson's Disease
Pharmaceutical Raw Materials Cabergoline 81409-90-7 Used To Parkinson's Disease
Basic Info.
Cabergoline
Alias: Cabaser, Dostinex; Dostine, 6-Allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide
CAS: 81409-90-7
Molecular Formula: C26H37N5O2
Molecular Weight: 451.6
Melting Point: 102-104° C
Purity: 99%
Character: White Powder
Packing: Foil bag or as requirments
Description:
Cabergoline is a dopamine agonist designed to reduce prolactin. In medical circles it is commonly used to combat prolactinomas, a benign tumor of the pituitary gland that may cause an excess production of prolactin. It is also used by athletes who supplement with anabolic steroids that may increase prolactin levels
Cabergoline, most commonly sold under the brand name Dostinex, is not a new drug as it was first developed in 1981 by the Italian drug manufacture Farmitalia-Carlo Erba Spa. The drug was later acquired by Pharmacia and then found its resting place with Pfizer in 2002.
Cabergoline Functions and Traits:
As a dopamine agonist, Cabergoline directly correlates with the long acting D2 receptor thereby inhibiting the secretion of prolactin in the body and in turn lowering serum prolactin levels. As a dopamine agnonist, Cabergoline is used to treat Parkinson's disease, hyperprolactinaemia (abnormally high levels of prolactin in the blood), Cushing's disease and as mentioned prolactinomas.
Cabergoline's direct function (specifics) is in that it inhibits prolactin secretion in the pituitary's lactotroph cells. It really is a very simple drug and what's simpler or perhaps interesting is that the simple medication was discovered almost accidently during experiments with ergot alkaloids.
Uses in medicine:
There are many uses that the medical world is discovering for dostinex. They include hyperprolactinemia, prolactin producing tumors, Parkinson's disease, Cushing's disease, and a myriad of other ailments.
One of the best known uses for cabergoline is in tumors and cancers related to high prolactin levels. In fact, it's been an industry leading drug when it comes to shrinking prolactin-secreting macroadenomas.
Bodybuilding Uses:
There are several ways we can use caber in bodybuilding. Since it is a dopamine agonist, some athletes believe they can take it to give themselves an adrenaline rush during a sporting event. Also, the addition of dopamine can improve motor skills and give you an edge over your competition. In theory, you will be able to workout much harder and be able to ignore pain pushing your muscles to the limit.
The main way bodybuilders use cabergoline is when they run a compound which increases prolactin levels in the body. Trenbolone will turn into prolactin, and, when abused, you can get prolactin based gynecomastia. In addition, a spike in prolactin can cripple your sex drive. Even when you do not run a compound that increases prolactin, caber can still help normalize your libido when you are playing with your hormones.
Another way caber can be used in bodybuilding is by its mechanism of mimicking dopamine being produced from food intake. Ever had a craving for New York style greasy pizza, oreo ice cream or some other treat you know you shouldn't have? Well, when you take cabergoline, the dopamine being released can act as the pleasure chemical, which can make a bite of that pizza satisfy you rather than eating the whole pie. This aids weight loss goals and helps you stay lean.
And finally, sleep! Many bodybuilders who take cabergoline report improved sleep thanks to the dopamine mimic. This allows you to sleep more, deeper and longer.
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