Pharmaceutical Raw Materials Respiratory System Drugs Roflumilast for COPD

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Pharmaceutical Raw Materials Respiratory System Drugs Roflumilast for COPD



Basic Info.

Roflumilast
Synonyms: ROFLUMILAST;3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide;B 9302-107;BY 217;BYK 20869;Daxas;Roflumilast / 3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide;3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
CAS:
MF: C17H14Cl2F2N2O3
MW: 403.21
MP: 158°C
storage temp. Refrigerator
Chemical Properties Crystallin Solid
Usage Selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease
Purity: 99%
Usage: API
Package: 1KG foil bag; 25Kg drum


Description:

Roflumilast is a phosphodiesterase-4 (PDE-4) inhibitor. Due to its selective inhibition of the PDE4 isoenzyme in lung cells, roflumilast is indicated for the management of chronic obstrtuctive pulmonary disease (COPD) exacerbations. Treatment with Roflumilast is associated with an increase in psychiatric adverse reactions, including suicide and suicidal attempts.

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