Solid Phase Peptide Synthesis

• 

Peptide Synthesis Resins

Since Solid Phase Peptide Synthesis was first proposed by Robert Bruce Merrifield, the method of synthetic peptides became more popular than liquid phase peptide synthesis because of high efficiency. This method could assemble a peptide chain rapidly through successive reactions of amino acid derivatives on an insoluble support.

The original peptide antibiotics are also biosynthesized and extracted from the culture of polymyxa or aeruginosa. Another synthetic method of peptides is chemical synthesis, which is divided into liquid phase chemical synthesis and solid phase chemical synthesis. The liquid phase method is mainly used for the synthesis of short peptides. The solid phase synthesis method can be used to prepare long-chain peptides, cyclic peptides, and complex. Peptide. The solid phase method is divided into a Boc method and an Fmoc method. It requires the solid phase synthesis of the carrier to achieve the growth of the peptide chain by means of stepwise amino acid condensation. The advantages of solid phase synthesis are ease of purification, shortening of the synthesis cycle, and ease of automation.

Solid phase peptide synthesis(SPPS) support consists of small, polymeric resin beads functionalized with reactive group such as amine or hydroxyl groups, which link to systhesis peptide chain step by step.

Solid phase peptide synthesis(SPPS) resins is insoluble in all common solvents but swells well in most organic solvents. Better swelling degree is benefit for the reaction yields, but for short peptide easy to synthesis, lower swelling degree will be suitable and it will be good at saving solvent.

Solid phase peptide synthesisResins are rich in variety, complete in specifications and stable in performance.

Typical Applications

Solid phase synthesis of Bivalirudin

Solid phase synthesis of Eptifibatide

Solid phase synthesis of Exenatide

Solid phase synthesis of Liraglutide

Solid phase synthesis of thymopentin

Solid phase synthesis of Thymalfasin

Solid phase synthesis of Buserelin

Solid phase synthesis of Goserelin

Solid phase synthesis of Octreotide

Solid phase synthesis of Calcitonin

Our Customized Service

We also have good experiences in research and develop the amine acid pre-loading peptide resins, and we have extended resin backbone to hydrophilic matrix, such as DEG series, TEG series, PEG series. Welcome to ask for Sunresin!

Другие товары поставщика

	Size Exclusion Chromatography Media	Category List Seplife®4B Agarose matrix, 4% content, Equivalent to Sepharose 4B. Seplife®6B Agarose matrix, 6% content, Equ...
	Mixed Bed Ion Exchange Resin	SEPLITE ® Mixed Bed Ion Exchange Resin Mixed bed is typically cation and anion ion exchange resin all in one mixture. Mixed bed ion exchange ...
	Strong Base Anion Exchange Resin (SBA)	SEPLITE ® Strong Base AnionExchange Resin The Strong Base Anion Exchange Resin is the type of ion exchange resin with functional group of quat...
	Cane Sugar Refining 21	Ion Exchange Technique for Sugar Decolorization Resinand Deashing The usual process of cane sugar is extraction, purification, evaporation, concen...
	Enzyme Carriers	SEPLITE®Enzyme CarriersEnzyme carrier is a kind of Resin beads for Enzyme immobilization.The enzyme catalysis technology mainly relies on the h...

Похожие товары

	Acrylic Design Artwork Cutting	Продавец: Beijing KangDa ShengXin Acrylic Products Co., Ltd	Acrylic Design Artwork Cutting PRODUCT DESCRIPTION We specialize in custom acrylic high process...
	Custom Cut Plastic Sheets	Продавец: Beijing KangDa ShengXin Acrylic Products Co., Ltd	Custom Cut Plastic Sheets PRODUCT DESCRIPTION professional acrylic sheet factorywith 16 years...
	Clear Acrylic Display Rack	Продавец: Beijing KangDa ShengXin Acrylic Products Co., Ltd	Clear Acrylic Display Rack Product Description Acrylic Riser Display Stand Change-4 Tier Clear ...
	Professional Clear Acrylic Cosmetic Stand Make-Case	Продавец: Beijing KangDa ShengXin Acrylic Products Co., Ltd	Professional Clear Acrylic Cosmetic Stand Make-Case Product Description Acrylic cosmetic organi...
	Acrylic Wedding Table Sign	Продавец: Beijing KangDa ShengXin Acrylic Products Co., Ltd	Acrylic Wedding Table Sign Product Description Acrylic/Plexiglass Clear Wedding Signs A5 Made ...